Ashwagandha

• Supports the body's stress response through HPA axis modulation*
• Supports a healthy cortisol response*
• Formulated at the dose and form used in clinical research — 600mg full-spectrum root extract*

Chandrasekhar, K. et al. (2012) — Indian Journal of Psychological Medicine 

A randomized, double-blind, placebo-controlled trial in 64 adults with chronic stress found that 600mg/day of full-spectrum ashwagandha root extract over 60 days was associated with significant reductions in serum cortisol compared to placebo.

What this means for this formulation: This is the foundational trial, and it used the same dose and form as BdyAlign Ashwagandha — 600mg of full-spectrum root extract. It's the study the rest of the research base is anchored to.

Bachour, G. et al. (2025) — BJPsych Open 

A systematic review and meta-analysis of 15 randomized controlled trials in 873 participants found ashwagandha supplementation was associated with statistically significant reductions in cortisol at 8 weeks.

What this means for this formulation: This is the most current and comprehensive synthesis to date. It confirms the cortisol finding across a large pooled population — which is why cortisol modulation is the most reliable claim in this category.

Albalawi, A.A. et al. (2025) — Nutrition and Health 

A meta-analysis confirmed a significant reduction in cortisol but found no significant effect on perceived stress.

What this means for this formulation: This is the honest nuance most supplement marketing skips. The cortisol-modulation finding is robust; the effect on felt stress is more variable. We'd rather tell you that than overpromise — the research most reliably supports the cortisol pathway, and the subjective experience of it varies from person to person.

Long-term safety (2025) — Phytotherapy Research 

A 12-month prospective study in 191 adults reported a favorable safety profile across hepatic, renal, and thyroid laboratory parameters.

What this means for this formulation: Ashwagandha is well-studied for daily use, and the long-term data supports its tolerability. The most commonly reported effects are mild.

The studies cited above are classified as Level B evidence — strong meta -analytic support for cortisol modulation, with more variable findings on subjective stress. Individual results vary based on baseline stress, dosage consistency, and lifestyle factors.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. If you have a thyroid condition, an autoimmune condition, are taking sedatives, immunosuppressants, thyroid medications, or any prescription medication, or are pregnant or breastfeeding, consult a healthcare provider before use.

Active ingredient:

Resveratrol Complex (Polygonum cuspidatum)(root) — 600mg, standardized to 50% trans-resveratrol. Trans-resveratrol per serving: 300mg.

Other ingredients:

Vegetable capsule (cellulose), Microcrystalline Cellulose

Why Japanese Knotweed root — and why the 50% standardization matters:

Resveratrol occurs naturally in red wine and grapes, but at very low concentrations — a glass of red wine contains roughly 0.3–2mg. Japanese Knotweed root is the highest-concentration natural source, which is why it's used in most resveratrol supplements studied in research. The 50% standardization means half the complex weight is confirmed trans-resveratrol — the form most studied in research. An unstandardized resveratrol supplement has unknown trans-resveratrol content.

What's Not In It:

• No proprietary blends — single active ingredient, fully disclosed dose
• No artificial fillers
• Plant-derived capsule (cellulose)
• Vegan

Manufactured in an FDA-registered, cGMP-compliant facility in the US

Take one (1) capsule twice a day as a dietary supplement. For best results, take 20-30 min before a meal with an 8oz glass of water or as directed by your healthcare professional.

For the Rooted One — how this fits your daily practice:

If your stress has been running high for years rather than days, the effects accumulate — and so does the work of unwinding it. Ashwagandha isn't an acute fix. It's studied for its role in supporting how your body responds to stress over time, through the HPA axis, and the research timeline reflects that: meaningful change shows up over weeks of consistent use, not in a single dose.

Take your two capsules consistently — many people anchor them to a meal so the habit holds — and treat the supplement as one layer of a larger practice, not the whole thing. The nervous system work, the sleep, the boundaries you hold: those are the practice. Ashwagandha supports the regulatory system underneath it. The consistency is what makes the research timeline work for you.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Q: How long until I notice a difference? 

A: Ashwagandha works on the long arc, not the short one. The foundational research used a 60-day window, and the 2025 meta-analysis confirmed effects on cortisol at 8 weeks — so 4 to 8 weeks of consistent daily use is the realistic timeline. One honest note: research most reliably supports ashwagandha's effect on cortisol; the effect on how stressed you feel is more variable from person to person.

Q: I take other supplements or medications. Is this safe? 

A: Ashwagandha has more considerations than most adaptogens. If you have a thyroid condition or an autoimmune condition, are taking sedatives, immunosuppressants, thyroid medications, or any prescription medication, or are pregnant or breastfeeding, consult your healthcare provider before use. A 12-month study found a favorable safety profile across liver, kidney, and thyroid markers in healthy adults, but the contraindications above are real — please don't skip that conversation with your provider if any apply to you.

Q: Why should I subscribe instead of buying one-time? 

A: Because the research timeline is weeks of consistency, not occasional use. Ashwagandha's studied effects build over 4 to 8 weeks of daily intake — skipping stretches extends that. Subscribe & Save gives you 15% off monthly and 20% off 90 day delivery with the ability to skip or cancel anytime. There's no contract and no penalty for canceling. The discount is there because we'd rather you stay consistent than run out mid-month.

Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Warning: This product is not intended to diagnose, treat, cure or prevent any disease. Keep out of reach of children. Do not use if the safety seal is damaged or missing. Store in a cool, dry place.